Persufflation (or gaseous oxygen perfusion) as a method of organ preservation
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منابع مشابه
Persufflation (or gaseous oxygen perfusion) as a method of organ preservation.
Improved preservation techniques have the potential to improve transplant outcomes by better maintaining donor organ quality and by making more organs available for allotransplantation. Persufflation, (PSF, gaseous oxygen perfusion) is potentially one such technique that has been studied for over a century in a variety of tissues, but has yet to gain wide acceptance for a number of reasons. A p...
متن کاملPersufflation (gaseous oxygen perfusion) as a method of heart preservation
Persufflation (PSF; gaseous oxygen perfusion) is an organ preservation technique with a potential for use in donor heart preservation. Improved heart preservation with PSF may improve outcomes by maintaining cardiac tissue quality in the setting of longer cold ischemia times and possibly increasing the number of donor hearts available for allotransplant. Published data suggests that PSF is able...
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BACKGROUND Early graft dysfunction due to preservation/reperfusion injury represents a dramatic event after liver transplantation. Enhancement of donor organ criteria, in order to cope with the ever increasing donor shortage, further increases graft susceptibility to ischemic alterations. Major parts of post-preservation injury, however, occur at the time of warm reperfusion but not during isch...
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BACKGROUND One of the most restricting factors remaining in heart transplantation is the limited myocardial ischemia time. A new approach towards the prolongation of this time is the combination of primary cardioplegic arrest followed by continuous coronary oxygen persufflation (COP) with gaseous oxygen. METHODS This technique was applied in pig hearts, which we transplanted orthotopically af...
متن کاملHaemoglobin, oxygen carriers and perioperative organ perfusion.
Under normal conditions, only 20-30% of the delivered oxygen is metabolised. In normovolaemic anaemia, the organism reacts with increases in cardiac output and oxygen extraction. Once these mechanisms are exceeded, allogeneic blood transfusions may be administered. However, such transfusions are associated with serious adverse effects and alternatives such as artificial oxygen carriers are bein...
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ژورنال
عنوان ژورنال: Cryobiology
سال: 2012
ISSN: 0011-2240
DOI: 10.1016/j.cryobiol.2012.01.007